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The core protective effects of citrulline are largely exerted through its metabolite NO, which operates via three interrelated mechanisms: first, by inhibiting the mitochondrial translocation of the fission protein Drp1, thereby preserving mitochondrial structural integrity

Am J Physiol (1997) 272:E9526

Losol P, Wolska M, Wypych TP, Yao L, O'Mahony L, Sokolowska M

Role of renal tubular programed cell death in diabetic kidney disease

I mean, I use the guy to dot the I's and cross the T's, but I have zero (ZERO) faith in the medical community after the last 20 years and almost zero in pharma as well